An evolving understanding of the relationship between drugs and the brain is contributing to a paradigm shift in drug policy, defined by measures to help keep individuals with addiction alive as the long path toward recovery takes course
Significant harm-reduction potential exists in increasing access to medication assisted treatment (MAT) – the most effective approach for managing opioid use disorder, but which less than 20% of affected individuals in the U.S. receive
Developments in the neuroscience of targeted brain stimulation and brain-based risk prediction represent novel treatment and prevention strategies on the near-horizon
Article Summary
While pre-COVID-19 data indicated that the massive public health effort to fight the opioid epidemic was beginning to gain ground, the record-breaking surge of overdose deaths during the pandemic revealed that the underlying state of our addiction prevention and care system remains insufficient. This reality has demanded a rethinking of approaches – both policy-based and scientific – to accelerate the reversal of the crisis. Evolving harm reduction policies based in a greater appreciation for the neuroscience of addiction represent a positive shift in our approach to addressing addiction. Yet, there is still much opportunity for improvement, especially in expanding the use of medication assisted treatment (MAT) to treat opioid addiction. Moreover, emerging neuroscience research may offer new paths to treatment and prevention. Collectively, these efforts have the potential to significantly tip the balance in the battle against drug addiction in America.
*Email: ckorponay@mclean.harvard.edu
Open Access
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Cole Korponay
Department of Psychiatry, Harvard Medical School, Cambridge, MA